The grip strength meter allows the study of neuromuscular functions in rodents by determining the maximum force displayed by an animal. This test is included in the Functional Observational Battery (FOB) to screen for neurobehavioral toxicity. In this context, changes in grip strength are interpreted as evidence of motor neurotoxicity.
Basically, the grip strength meter is positioned horizontally and the subjects are held by the tail and lowered towards the apparatus. The animals are allowed to grasp the metal grid or triangular pull bar and are then pulled backwards in the horizontal plane. The force applied to the grid or to the bar just before it loses grip is recorded as the peak tension. This force can be measured in grams, Newtons or Ibs.
The grip test includes one accessory by default (bar for rat, grid for rat, bar for mouse or grid for mouse). A different part number is available depending of the included accessory chosen by the customer. The other available accessories can still be added if needed.
Data output is carried out through RS232, printer, or chart recorder. Depending on the grid type used, grip strength can be measured from the front or hind paws.
The SEDACOM 2.0 or BIO-CIS software provides an easy and convenient way to visualize and export the data on a computer for further analysis.