Test de la rueda de actividad - ejercicio voluntario

Descripción

Soluciones Integradas relacionadas

Descripción

The rodent Activity Wheel represents a very simple and clever way to register animal physical activity in its home cage environment.

The use of this high throughput tool is particularly relevant for research involving circadian rhythms, phenotyping and drug testing. Typically, the time and distance run on a voluntary running wheel are monitored over several days or weeks to determine whether a particular substance or experimental manipulation has an effect on exercise behaviour.

Soluciones Integradas relacionadas

RUEDA DE ACTIVIDAD - SEDACOM (Panlab)

Rueda de actividad
SEDACOM software

Razones para elegir este test

Rodent voluntary exercise registering: allows animals to exercise when and at the intensity that they choose
Availability of a running wheel may reduce the effects of chronic stress on depression-like signs in mice
Less labour intensive than treadmill running because researchers need not be present during wheel running
Relatively inexpensive setup
Ideal for high throughput experiments: many animals can be trained at the same time
Sensitive for both rats and mice

Razones para no elegir este test

The researcher cannot control the intensity and duration of exercise
Certain lines of transgenic mice may not engage in enough voluntary wheel running exercise to produce training adaptations
No suitable for studies that require precise timing to explore acute postexercise adaptations (intermittent running throughout the active cycle)
Cancer

Enfermedades/aplicaciones humanas relacionadas

Drug screening
Phenotyping
Neuromuscular diseases
Parkinson disease
Duchenne muscular dystrophy

Áreas de investigación

Actividad & Exploración